Commonly used biomarkers to predict response to checkpoint inhibitors include tumoral PD-L1 expression and presence of high tumor mutation burden (TMB), deficient mismatch repair (dMMR)/high microsatellite instability (MSI-H); however, the PD-L1, TMB, and dMMR/MSI-H status of these patients was and is unknown. The gene discussed is CD274; the disease is neoplasm.