The protein expression of angiogenesis-related genes such as CCNE1, a disintegrin and metalloprotease 17 (ADAM17), mevalonate diphosphate decarboxylase (MVD), SMA_MVD, VEGFA, VEGFB, VGFR2, HIF-1α in tumor tissues was explored (Fabbi et al., 2022). Here, HIF1A is linked to neoplasm.