Benefits of PD-1 inhibitors were documented for patients with other subtypes of B cell lymphomas, including four patients with r/r primary central nervous lymphoma, one patient with primary testicular lymphoma (Nayak et al., 2017), and three patients with mediastinal gray-zone lymphoma (Melani et al., 2017). The gene discussed is PDCD1; the disease is B-cell non-Hodgkin lymphoma.