A previous study reported that the population of IM (CD14++CD16+) cells was higher in PBMCs from BD patients than in those from NCs, and the population of NCM (CD14+CD16++) cells was lower in these patients; furthermore, the populations of both cells were related to the ESR and CRP levels (Li C et al., 2021). The gene discussed is ESR1; the disease is Behcet disease.