TOB1, which codes for an antiproliferative protein that targets mRNA deadenylation and decay (Hosoda et al., 2011), has previously been associated with neurodegenerative disorders (Weskamp and Barmada, 2018), such as multiple sclerosis (Gironi et al., 2016) and a TOB1 deletion has been associated with hippocampus-mediated acute stress response in animal models (Youssef et al., 2022). The gene discussed is TOB1; the disease is multiple sclerosis.