To investigate the expression level of SPON2 in TNBC, we performed immunohistochemical experiments on 12 cases of TNBC and its paraneoplastic normal samples and 20 cases of breast fibroadenoma, and the results showed that the expression of SPON2 was higher in TNBC than in the paraneoplastic normal tissue and breast fibroadenoma, Figures 1A, B. Here, SPON2 is linked to Fibroadenoma.