To assess γH2AX foci, LNCaP (AR+) and DU145 (AR-) prostate cancer cells were treated with JNJ-64619178 for 4 days, then the cells were exposed to 2 Gy of X-ray (IR+) for inducing DSBs, next the cells were incubated for 6hrs to let them employ repair proteins at the site of DSBs (22). This evidence concerns the gene AR and prostate carcinoma.