In conclusion, six potential immune-related prognostic predictors or biomarkers including two abnormal miRNAs (hsa-miR-125b-5p and hsa-miR-21-5p) and four targeted genes (NTF3, PSMD14, CD320, and SORT1) were identified in HCC, which may be closely correlated with the infiltration of immunocytes. The gene discussed is SORT1; the disease is hepatocellular carcinoma.