The mRNA expression of CD320 and PSMD14 was significantly upregulated in six HCC cell lines (HCCLM3, MHCC97H, Hep3B, Huh7, PLC/PRF/5, and HepG2) compared to liver cells L02 (Fig. 9B-a, b). The gene discussed is PSMD14; the disease is hepatocellular carcinoma.