These data suggest that SPD may be more important in PWH with lower CD4 + counts, and though we analyzed a group of PWH with untreated HIV, very few participants reached CD4 + counts as low as these previous studies because ART was initiated at a CD4 + count of 350 cells/mm3, and the study was terminated early at which time all participants were offered ART28. The gene discussed is CD4; the disease is Platelet storage pool disease.