The results showed that the frequency of CHSY1 in MLS was 25%, which was lower than that of other histologic types including myxofibrosarcoma, malignant peripheral nerve sheath tumor, and low-grade fibromyxoid sarcoma; however, the expression was limited to those showing round cell morphology indicative of poor patient prognosis. The gene discussed is CHSY1; the disease is McLeod neuroacanthocytosis syndrome.