Furthermore, PMBCs were isolated from the first two CML patients, of which PBMCs from Patient 1 expressed a higher level of BCR-ABL1 than Patient 2 (Fig. 7f, g), and were subjected to assessing TGF-β-induced p57 expression. Here, TGFB1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.