Although there was no change in the proportion of CD4+ T cells (Supplementary Fig. 25C and S29), the percentages of tumor-infiltrating CD3+ T cells (Supplementary Fig. 25D and S30), CD8+ T cells (Fig. 6G and S31), IFN-γ+CD8+ effector T cells (Fig. 6H) and B cells (Fig. 6I and S32) were significantly increased in G7 compared with those in G1, G4, and G6. Here, CD4 is linked to neoplasm.