However in non-DeepSNiF denoised DIMR data, the trends between B cells has been violated from MDS to AML by DIMR data (P = 0.4923), as well as those from Normal to MDS between CD4 and CD8 T cells (P = 0.4762), and CD4 T to B cells (P = 0.6685). This evidence concerns the gene CD4 and acute myeloid leukemia.