We and others reported that AML1-ETO caused “BRCAness” phenotype in leukemia cells [35, 38], but loss of ABL1 expression did not sensitized leukemia cells to PARPi olaparib and RAD52i 6-hydroxy-DL-Dopa (Fig. 4A, B, PARPi and RAD52i). The gene discussed is RUNX1; the disease is leukemia.