CEACAM5 and neoplasm: As shown in Table 2, for GC patients with LVI/PNI‐positive disease, higher CEA level (p = 0.019), higher CA199 level (p < 0.001), deeper tumor invasion (p < 0.001), more LNM (p < 0.001), and advanced TNM stage (p < 0.001) were noted compared to those with LVI/PNI‐negative disease.