The numerous Tregs produce more anti‐inflammatory IL‐10 inhibiting colitis‐associated colorectal cancer.[49] Propionate produced by the gut microbiota also inhibits HDAC reducing the secretion of IL‐17 and IL‐22 by γδT cells to suppress colon cancer.[50] Despite SCFAs having potent anticancer abilities, in certain circumstances, they might promote cancer progression. Here, HDAC9 is linked to malignant colon neoplasm.