This autocrine stimulation further activates mitogen‐activated protein kinase (MAPK) signaling, promoting the progression of gastric cancer.[27] In addition, miR‐181a‐5p‐rich extracellular vesicles are released from colorectal cancer cells activating IL‐6/ signal transducers and activators of transcription 3 (STAT3) signaling in hepatic stellate cells. Here, STAT3 is linked to colorectal cancer.