MTOR and colonic neoplasm: Large amounts of secondary bile acids impair the immune ability of natural killer T cells to promote tumor growth.[11] In the case of colon cancer, enterotoxigenic Bacteroides fragilis activates mTOR signaling mediated by the long non‐coding RNA BFAL1 to accelerate tumor growth.[12]Fusobacterium nucleatum promotes the secretion of interleukin (IL)‐8 and C‐X‐C motif chemokine receptor 1 (CXCL1) supporting the proliferation and migration of HCT116 cells.[13] Thus, the microbiome plays an increasingly crucial role in tumor progression and cancer treatment.