In APCMin/+ mice, this leads to an increase in the number of regulatory T (Treg) cells and interleukin (IL)‐10 producing CD4+ T cells and a decrease in that of T helper 17 (Th17) cells.[37] The APCMin/+ mouse is a well‐known animal model employed in studies on human colon cancer. Here, IL10 is linked to malignant colon neoplasm.