AGT and triple-A syndrome: To aid comparison, data from saline or AngII-treated hampfl/fl or hampfl/fl, SMMHC-CreERT2+ mice shown previously in Figure 2 are shown again, where appropriate, in Figure 4G through 4L. Together, these data demonstrate that suppression of local LCN2 expression contributes to the protective effect of raised SMC-derived HAMP in the setting of AAA, and that this protective effect likely involves promoting reparative autophagy in SMCs and reducing neutrophil infiltration into the aortic wall