When analyzing TCGA GBM samples, however, we saw that only the PRKRA/CHROMR ratio (Figure 3C), but not CHROMR (Supplementary Figure S2E) or PRKRA (Supplementary Figure S2H) separately, had prognostic value: GBM patients who had a high PRKRA/CHROMR ratio had a significantly lower hazard ratio (HR = 0.54, p = 0.0074). The gene discussed is PRKRA; the disease is glioblastoma.