For example, miR-27b, which CHROMR seems to be able to sponge (Hennessy et al., 2019) has both been linked with glioma progression (Chen et al., 2011; Liu et al., 2015; Miao et al., 2020) and glioma repression (Chang et al., 2020; ZHAN et al., 2021). Here, CHROMR is linked to central nervous system cancer.