Fifthly, elevation in CRP expression may promote the synthesis of coagulation factors, which may potentially lead to a hypercoagulable state in the affected patients, leading to the formation of DVT and the aggravation of the disease.21 In the present study, further analysis of the diagnostic efficacy of ROC curve revealed that TM, TG, D-D and Fb had higher sensitivity (>80% in all) to the formation of DVT, yet with relatively reduced diagnostic efficacy of CRP. This evidence concerns the gene CRP and deep vein thrombosis.