Several are in proximity to known T-ALL genes, such as Myb, Myc, and Ptprc. 54,55,56 Others are potential regulators of transcription factors and signaling genes, such as Fam126a, Il6st, and Kctd1, which have so far not been implicated in T-ALL (Data S2). This evidence concerns the gene PTPRC and T-cell acute lymphoblastic leukemia.