In order to further investigate the role of IFIT1 and PARM1 in patients with osteosarcoma, we analyzed the expression and prognostic effects of IFIT1 and PARM1 in patients with osteosarcoma, using the risk scores of IFIT1 and PARM1. IFIT1 expression was significantly increased in osteosarcoma tissues compared to normal tissues (Figure 4A), and patients with low IFIT1 expression had a better prognosis (Figure 4B, p=0.07). Here, PARM1 is linked to osteosarcoma.