LDLR and coronary artery disorder: To further examine the expression pattern of the CAD risk locus murine equivalent in an inflammatory cell context, we measured the expression of three Ak148321 exons and four expected circular isoforms in the spleens of Chr4Δ70kb/Δ70kbLdlr−/−ApoB100/100 and Ldlr−/−ApoB100/100 mice on the standard laboratory diet and in response to prolonged HFD (Figure 6A).