Because both global and hematopoietic deletions in the murine CAD risk orthologous locus led to increased atherosclerosis, global Chr4Δ70kb/Δ70kbLdlr−/−ApoB100/100 mice showed increased blood leukocyte count, and Chr4Δ70kb/Δ70kb BMDMs showed more pro-inflammatory phenotype in vitro, we decided to investigate if human ANRIL and its murine equivalent (Figure 5A) are expressed in inflammatory cell populations in atherosclerotic plaques, and how their expression levels are in comparison with other vascular cell populations. Here, CDKN2B-AS1 is linked to atherosclerosis.