CDKN2B-AS1 and coronary artery disorder: In this study, we aimed to clarify the systemic and hematopoietic cell-specific effects of the CAD risk locus both on early and advanced atherosclerosis by using a mouse model having the Chr4Δ70kb/Δ70kb deletion orthologous to human CAD risk locus, including the middle exons of the murine ANRIL equivalent, Ak148321, in a more human-like atherosclerotic mouse model.