AGT and hypertensive disorder: For example, rs5051 in AGT is found to be associated with blood pressure lowering to beta-blockers in 115 Swedish patients with hypertension and left ventricular hypertrophy (Kurland et al., 2004) but with blood pressure lowering to ACEIs in 640 Chinese patients with essential hypertension (Kurland et al., 2004; Yu et al., 2014).