GPT and cholestasis: Literature research shown that, ALT and AST in serum as the main indicators reflecting liver function, can directly reflect the damage and degree of liver cells (Xie et al., 2015; Han et al., 2019); ALP and γ-GT were specific and important markers of cholestasis because they cannot be excreted into the blood by the biliary system after liver dysfunction, which lead to the increase of serum content (Yue et al., 2014; Berköz et al., 2021).