IFNG and pancreatic ductal adenocarcinoma: Immune-related pathways such as inflammatory response, interferon-gamma response, and epithelial-mesenchymal transition were significantly activated in the aggressive C3 subtype compared to other cases; cell cycle-related pathways were also significantly upregulated in C3, indicating that immune activation was associated with prognosis of pancreatic ductal adenocarcinoma was negatively correlated.