There was almost no difference in the density of total DCs between the EGFR-19del tumor-bearing mice and the EGFR-WT ones, but DCs from the EGFR-19del group had a lower expression level of MHC-II and produced much less IL-12p40, which could enhance the downstream cytotoxic immune response, indicating that less activity of DC was shown in the EGFR-19del tumor (24). Here, EGFR is linked to neoplasm.