LCN2 and Cognitive impairment: In model 1, after adjusting the confounding of age, sex and education level, it was suggested that serum NGAL was a risk factor for SCI-related cognitive impairment (p < 0.05); in model 2, we further adjusted the Smoking and drinking suggest that serum NGAL is also a risk factor for SCI-related cognitive impairment (p < 0.05); Serum NGAL was found to be an independent risk factor for cognitive impairment caused by SCI in model 3, which was based on model 2.