Previous studies have found that DLAT colocalizes with autophagy markers LC3 and SQSTM1 among patients with primary biliary cirrhosis (PBC), and the autophagy induced in bile epithelial cells is related to the over-expression of DLAT (Sasaki et al., 2013; Zhang et al., 2020). Here, SQSTM1 is linked to primary biliary cholangitis.