Still, we would like to provide some hints: (i) the T‐helper cells give signals to cytotoxic lymphocytes within a tumour to establish antitumor immunity; (ii) an increase in CD3+, CD4+ and CD8+ cells were detected in some cancers; (iii) the NKT cells may either eliminate cancer cells or, if overstimulated, they may become ineffective.46, 47, 48. The gene discussed is CD8A; the disease is cancer.