WASF3 and breast cancer: Generation of the phospho-mutant WAVE3 (W3-Y4) at tyrosine residues Y151, Y248, Y337 and Y486 (Additional file 1: Fig. S1A) has been described and thoroughly tested in our previous publications [17, 18], as was the generation of WAVE3-deficient BC cell lines, including MDA-MB-231 and 4T1, using CRISPR/Cas9 mediated gene knock-out [11, 14, 18].