WASF3 and in situ carcinoma: Tumors derived from CIS-R-W3KO, which also expressed significantly low levels of β-Catenin, grew much slower than their CIS-R counterparts, started regressing and continued to regress during the chemotherapy treatment, clearly establishing a key role of WAVE3/β-catenin (loss of expression of WAVE3 and β-Catenin) in sensitizing TNBC tumors to chemotherapy.