Results exhibited that the protein levels of ENO2, PFKP, PLIN2, TRIB3, RIMKLA, PLOD2, GMPPA, and HYI were higher in ccRCC, while the protein levels of METAP1 and GALNT7 were lower and the protein level ITPKB remained the same, in comparison with normal kidney tissues (Fig. 11C). The gene discussed is HYI; the disease is nonpapillary renal cell carcinoma.