We subsequently analyzed ZBTB4 protein expression in pancreatic cancer tissue microarrays using immunohistochemical staining and scored the staining intensity using the histochemistry score (Fig. 6C) and found that ZBTB4 protein was low in pancreatic cancer tissues after comparison with paired paraneoplastic tissues (Fig. 6D). Here, ZBTB4 is linked to pancreatic neoplasm.