The results indicated that the following cell types were correlated with ZBTB4: CD8+ T cells, CD4+ T cells, T cell regulatory, B cells, neutrophils, macrophages, monocytes, myeloid dendritic cells, nature killer T cells, mast cells, cancer-associated fibroblasts, common lymphoid progenitor, common myeloid progenitor, endothelial cell, eosinophil, granulocyte-monocyte progenitor, hematopoietic stem cells, T cell follicular helper, T cell natural killer and Myeloid-derived suppressor cells(MDSC) (Fig. 3). The gene discussed is CD4; the disease is cancer.