COVID-19 is associated with many inflammation-related signaling pathways, such as interleukin-6/Janus kinase/STAT (IL-6/JAK/STAT) pathway, interferon (IFN) cell signaling pathway, tumor necrosis factor-α/nuclear factor-kappa (TNFα/NF-κB) pathway, toll-like receptor (TLR) pathway, T-cell receptor (TCR) pathway, etc. [54–56]. This evidence concerns the gene TNF and COVID-19.