Among these intersecting miRNAs, 10 miRNAs, including hsa-miR-15a-3p, hsa-miR-23a-5p, hsa-miR-26b-5p, hsa-miR-186-3p, hsa-miR-4433a-3p, hsa-miR-548aq-5p, hsa-miR-548d-5p, hsa-miR-576-5p, hsa-miR-580-3p, and hsa-miR-6850-5p, were down-expressed, this may be the reason for the high expression of OAS gene family in HF. Here, SMOC1 is linked to hydrops fetalis.