To determine the essential RBFOX2 splicing targets that regulate the metastatic process in PDA cells, we identified 114 RBFOX2-dependent alternatively spliced events that are regulated reciprocally in each comparison, with P values of less than 0.05 and |ΔPSI| greater than 10% (Fig. 3a,b, Extended Data Fig. 6 and Supplementary Table 6). This evidence concerns the gene RBFOX2 and Patent ductus arteriosus.