STX18 and congenital heart disease: Gene OR10H2 located in locus 19p13.12 and gene STX18-AS1 in locus 4p16.2 are associated with acute myeloid leukemia and congenital heart disease, and the SNPs that have been associated to DKD are rs11664515 (p = 2.27 × 10–6) and rs16836018 (p = 2.27 × 10–6), respectively40–42.