Two leading SNPs of the cytochrome P450 enzymes (CYP2B7P, rs4001941, p = 1.12 × 10–6; CYP4F24P, rs117074522, p = 2.27 × 10–6) that are involved in drug pharmacokinetics and response have also been associated with DKD in T2DM patients39. The gene discussed is CYP4F24P; the disease is type 2 diabetes mellitus.