Conversely, increased USP10 expression is closely associated with proliferation and metastasis in several tumors, such as non-small-cell lung cancer, chronic myeloid leukemia, colorectal cancer, prostate cancer, and hepatocellular carcinoma [24, 29–33], and is significantly correlated with a poor prognosis of GBM patients [29]. The gene discussed is USP10; the disease is glioblastoma.