CD8A and central nervous system cancer: A difference in survival, trending towards significance, was seen between WT (n = 11) relative to CD8 KO mice (n = 9; p = 0.06), implanted with kinome KO GL261 glioma cells (Fig. 1c), suggestive of CD8 T-cell-mediated selection in WT mice implanted with kinome KO GL261 glioma cells.