Unlike CHEK2, the T-cell compartment associated with the low CHEK1 expressing tumor cells showed no significant enrichment for “Interferon γ (IFN-γ) signaling” (p = 0.76) and “T-cell-mediated cytotoxicity pathway” (p = 0.18) as compared to the T cells from high CHEK1 expressing tumor cells (Supplementary Fig. 6a–c). The gene discussed is CHEK2; the disease is neoplasm.