In tauopathies like AD, significant hyper phosphorylation and cleavage of Tau variants can enter postsynaptic spaces to destroy long‐term potentiation within the hippocampal segment by regulating the Src family tyrosine kinase Fyn/N‐methyl‐d‐aspartate (NMDA) receptor complex (see Figure 1) [9]. Here, MAPT is linked to tauopathy.