IGF1 and COVID-19: A COVID-19-impaired insulin/IGF signaling pathway is also associated with the downregulation of various metabolic pathways including the citrate cycle, lipid metabolism, beta-oxidation, amino acid metabolism, carbohydrate metabolism, and respiratory electron transport chain affecting the adipose tissue, liver, lungs, and pancreas resulting in the development of multiorgan dysfunction (Shin et al., 2022).