LRP5 and gestational diabetes: IHC of LRP5 was significantly greater in villous cytotrophoblasts (h-score: 117.15 ± 32.17 and 84.41 ± 28.62, respectively; P < .001) and in endothelial cells of the villous vessels (h-score: 73.08 ± 28.74 and 46.47 ± 19.52, respectively; P < .001) of the placentas of pregnant women with GDM than in those without GDM (Tables 3 and 4; Figs. 3B and 4).