TCF7 and post-traumatic stress disorder: In another study by the same group, ChIPseq on six peripheral blood mononuclear cell samples of patients with PTSD compared with six samples of healthy controls, however, failed to reveal genome-wide alterations in H3K4me3 in PTSD, whereas on a gene-specific level H3K4me3 was found to be increased in PTSD patients around the promoter regions of the WNT10B, WNT10A, WNT7A, DVL1 and TCF7 genes [131].