HDAC2 and Anxiety: Infusion of the HDAC1 and HDAC2 inhibitor suberoylanilide hydroxamic acid (SAHA), also known as vorinostat, into the basolateral amygdala over seven days resulted in a significant induction of global H3 and H4 acetylation along with increased anxiety-like behavior in the open-field test and impairments in cue-dependent memory in a fear-conditioning paradigm [107].