There was no relation between PD-L1 expression in IC and the histopathologic features evaluated (depth of lamina propria invasion, long diameter of largest invasive focus, and the extent of lamina propria invasion or the presence of concomitant carcinoma in situ) (p = 0.313; p = 0.859; p = 0.603, p = 1.000, respectively). Here, CD274 is linked to in situ carcinoma.