High AKT2 mRNA expression was also substantially associated with a poor OS in patients with lung cancer (HR, 1.67; 95% CI, 1.41–1.97; P=1.2e−09) and patients with LUAD (HR, 2.35; 95% CI, 1.82–3.02; P=9.7e−12), but not in patients with SqCLC (HR, 1.35; 95% CI, 0.98–1.86; P=0.062) (Fig. 1D–F). The gene discussed is AKT2; the disease is lung carcinoma.