TP53MT was also associated with worse OS when we compared TP53 single hit to TP53WT in both AML (HR: 1.8 [1.42–2.46]) and MDS (HR: 1.3 [1.08–1.67]) but not in MDS/MPN subtype (Figs. 2C and 2D). Here, TP53 is linked to acute myeloid leukemia.