IL10 and infection: To identify whether Mø regulated by let-7b is a key modulator of intestinal fibrosis, peritoneal Møs obtained from IL-10−/− mice were transfected with let-7b agomir/antagomir in vitro and then these Møs were intraperitoneally injected into IL-10−/− mice 2 days after AIEC infection (Figure 5a).