ADNP overexpression has also been linked to the pathogenesis of germinal center B cell-type diffuse large B cell lymphoma (GCB-DLBCL); genome-wide screening of cancer-associated super-enhancers in this cell type and other human B cell lymphoma lines revealed the upregulation of ADNP, which is significantly associated with increased risk of death. The gene discussed is ADNP; the disease is diffuse large B-cell lymphoma.