Upregulated pathways were mainly enriched in steroid hormone biosynthesis, pyruvate metabolism, systemic lupus erythematosus, and autoimmune thyroid disease pathway, while downregulated pathways were mainly enriched in JAK-STAT signaling, tight junction, insulin signaling, and glycerophospholipid metabolism pathways. Here, SOAT1 is linked to systemic lupus erythematosus.