HP and anemia (phenotype): At baseline, all included patients had severe thrombocytopenia with median platelet count at 19 G/mL [10–37] G/L, mild regenerative anemia (hemoglobin: 9.6 g/dl [7.6–10], reticulocytes 178 [128–285]G/L) associated with hemolysis markers (median bilirubin: 36 μmol/L [23–59], haptoglobin: 0 g/dL [0–0.035]).