MS4A7 and glioblastoma: Since the RGS10 protein is located mainly on the inner side of the plasma membrane and does not have an extracellular segment that is essential for targeted therapy, the short isoform MS4A7-s, generated by the prognostic splicing event, ES of MS4A7 exon 3, was finally selected, which may play a critical role in GBM TME.