TF and breast cancer: Interestingly, when analysing TF binding sites from publicly available ChIP-seq data, SD48-specific FOXA1 peaks were highly enriched not only for FOXA1 binding sites, but also GATA3 binding sites (Fig. 5B), which could indicate a functional partnership between FOXA1 and GATA3 for regulation of the Luminal program, as suggested by Warrick et al. and described in breast cancer [14, 59].