In contrast, SE regions significantly bound at higher levels in the Basal tumours were associated with genes known to contribute to Basal cancer biology such as EGFR, but also less characterized genes with regards to bladder cancer biology, such as genes related to inflammation and FOXO signaling (IL7R, FBX032), signaling by Interleukin or signaling by MET, the activation of which is often correlated with BLCA progression [45] (Fig. 3E). Here, EGFR is linked to cancer.