SPI1 and bladder transitional cell carcinoma: In fact, we found that TFs associated with the Luminal network showed strong expression correlation in our dataset, TCGA-BLCA and in CCLE bladder cell cohorts [56] (Fig. S5A–C) while expression correlations of Stroma-Rich or Basal-associated TFs (e.g., ZEB1, SPI1) were lower for urothelial cell lines in the CCLE [57] compared to those found in primary tumours (Fig. S5A–C).